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Index > Protein center > FIBCD1(Gene name) > Human
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  • FIBCD1 (Gene name),
  • Fibrinogen C domain-containing protein 1 (Protein name ),  FBCD1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    FIBCD1(UNQ701/PRO1346);
    Protein name:
    Fibrinogen C domain-containing protein 1;
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homotetramer; disulfide-linked.
    Function:
    Acetyl group-binding receptor which shows a high-affinity and calcium-dependent binding to acetylated structures such as chitin, some N-acetylated carbohydrates, and amino acids, but not to their non-acetylated counterparts. Can facilitate the endocytosis of acetylated components.
    Subcellular Location:
    Membrane Single-pass type II membrane protein
    Protein Attributes:
    Sequence length:
    461
    Sequence:
    50:
    MVNDRWKTMG | GAAQLEDRPR | DKPQRPSCGY | VLCTVLLALA | VLLAVAVTGA | 
    100:
    VLFLNHAHAP | GTAPPPVVST | GAASANSALV | TVERADSSHL | SILIDPRCPD | 
    150:
    LTDSFARLES | AQASVLQALT | EHQAQPRLVG | DQEQELLDTL | ADQLPRLLAR | 
    200:
    ASELQTECMG | LRKGHGTLGQ | GLSALQSEQG | RLIQLLSESQ | GHMAHLVNSV | 
    250:
    SDILDALQRD | RGLGRPRNKA | DLQRAPARGT | RPRGCATGSR | PRDCLDVLLS | 
    300:
    GQQDDGVYSV | FPTHYPAGFQ | VYCDMRTDGG | GWTVFQRRED | GSVNFFRGWD | 
    350:
    AYRDGFGRLT | GEHWLGLKRI | HALTTQAAYE | LHVDLEDFEN | GTAYARYGSF | 
    400:
    GVGLFSVDPE | EDGYPLTVAD | YSGTAGDSLL | KHSGMRFTTK | DRDSDHSENN | 
    450:
    CAAFYRGAWW | YRNCHTSNLN | GQYLRGAHAS | YADGVEWSSW | TGWQYSLKFS | 
    461:
    EMKIRPVRED | R
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    Pfam:
    MIM:
    SMR:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human Fibrinogen C domain-containing protein 1
    Cat.:
    E8664h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human Fibrinogen C domain-containing protein 1
    Cat.:
    E8664m
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Fibrinogen C domain-containing protein 1
    Cat.:
    U8664h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Fibrinogen C domain-containing protein 1
    Cat.:
    U8664m
    Price:
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human Fibrinogen C domain-containing protein 1
    Cat.:
    P8664Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Fibrinogen C domain-containing protein 1
    Cat.:
    P8664Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Fibrinogen C domain-containing protein 1
    Monoclonal Antibody for Human Fibrinogen C domain-containing protein 1
    Protein for Human Fibrinogen C domain-containing protein 1
    Protein for Human Fibrinogen C domain-containing protein 1

    R&D Technical Data
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    Precision
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
      Clark H.F. , Gurney A.L. , Abaya E. , Baker K. , Baldwin D.T. , Brush J. , Chen J. , Chow B. , Chui C. , Crowley C. , Currell B. , Deuel B. , Dowd P. , Eaton D. , Foster J.S. , Grimaldi C. , Gu Q. , Hass P.E. , more...
      Genome Res.13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    2. 2.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
    3. 3.
      "DNA sequence and analysis of human chromosome 9."
      Humphray S.J. , Oliver K. , Hunt A.R. , Plumb R.W. , Loveland J.E. , Howe K.L. , Andrews T.D. , Searle S. , Hunt S.E. , Scott C.E. , Jones M.C. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Ashwell R.I.S. , Babbage A.K. , Babbage S. , Bagguley C.L. , more...
      Nature429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Brain.
    5. 5.
      "Characterization of FIBCD1 as an acetyl group-binding receptor that binds chitin."
      Schlosser A. , Thomsen T. , Moeller J.B. , Nielsen O. , Tornoee I. , Mollenhauer J. , Moestrup S.K. , Holmskov U.
      J. Immunol.183:3800-3809(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBUNIT;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    6. 6.
      "The recognition unit of FIBCD1 organizes into a noncovalently linked tetrameric structure and uses a hydrophobic funnel (S1) for acetyl group recognition."
      Thomsen T. , Moeller J.B. , Schlosser A. , Sorensen G.L. , Moestrup S.K. , Palaniyar N. , Wallis R. , Mollenhauer J. , Holmskov U.
      J. Biol. Chem.285:1229-1238(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBUNIT;IDENTIFICATION BY MASS SPECTROMETRY;MUTAGENESIS OF ASP-393; ASP-395; TYR-405; HIS-415; TYR-431; ALA-432 AND TRP-443
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